About the PANDA study
Chronic pain and Alzheimer’s Disease are related, major health concerns and that have increasing evidence supporting their overlapping etiologies and pathologies, and there is an urgent need to understand the mechanisms contributing to the development of these comorbid conditions as the population ages. Epigenetic modifications contributing to immune system dysfunction have been highlighted as a critical factor contributing to both chronic pain and AD/ADRD development. The proposed work will elucidate nutrigenomic mechanisms associated with related to pain and cognition, assess nutritional supplementation on epigenetic mechanisms related to pain and cognitive decline in older adults, and findings will have strong implications for advancement of pain management and AD/ADRD prevention strategies in older adult populations. The first phase of this study aims to assess thee variables in cognitively intact older adults with chronic knee an/or back pain. See this study on the NIH Reporter website.
Participate in the PANDA study
Enrollment for this study is now closed, but be sure to see if you are eligible for any of our other on-going studies.
Poster Presentations from the PANDA Study
Martinez, A., Montesino-Goicolea, S., Bell, K.L., Tamargo, J., Somerville, J.E., Cochran, J.Y., Sainterant, V., Cruz-Almeida, Y., and Strath, L.J. Exploring Sex Differences in the Associations of Carbohydrates with Chronic Pain and Physical Function in Adults with Knee Osteoarthritis: Preliminary Results from the PANDA Study”. The International Association for the Study of Pain World Congress 2024. Amsterdam, the Netherlands. August 5-9, 2024.
Publications from the PANDA study
Publications are currently in process – our lab members are currently crunching numbers and interpreting the data! While the NURTURE team is awesome, manuscripts take time to prepare and publish. Be sure to check back regularly for updates!